Patent revoked Patent revoked, The patent has been granted EP Register Verified

Use of a PCV2 immunogenic composition for lessening clinical symptoms in pigs

Publication No. EP2371383

•

App No. EP11164850

•

Filed by Boehringer Ingelheim Animal Health USA Inc.

•

Filed on 2006-12-28

•

Issued/Published on 2015-08-19

Official EPO Register

Publication No. EP2371383 A1

Application No. EP11164850 Filed: 2006-12-28

Grant Date 2015-08-19 Mention of grant

Active Oppositions 5 Active EPO Oppositions

Patent Abstract / Summary

[0001] The present invention relates to the use of an immunogenic composition that comprises a porcine circovirus type 2 (PCV2) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV2 infection. Preferably, they include lymphadenopathy, lymphoid depletion and/or multinucleated/giant histiocytes. Moreover, the clinical symptoms include lymphadenopathy in combination with one or a multiple of the following symptoms in pigs: (1) interstitial pneumonia with interlobular edema, (2) cutaneous pallor or icterus, (3) mottled atrophic livers, (4) gastric ulcers, (5) nephritis and (6) reproductive disorders, e.g. abortion, stillbirths, mummies, etc. Furthermore the clinical symptoms include Pia like lesions, normally known to be associated with Lawsonia intracellularis infections.

IPC Classifications

A61K39/12

Priority Claims

US 20050755016P Date: 2005-12-29

US 20060829809P Date: 2006-10-17

Designated Contracting States (31 EPC States)

Austria (AT)

Belgium (BE)

Bulgaria (BG)

Switzerland (CH)

Cyprus (CY)

Czech Republic (CZ)

Germany (DE)

Denmark (DK)

Estonia (EE)

Spain (ES)

Finland (FI)

France (FR)

United Kingdom (GB)

Greece (GR)

Hungary (HU)

Ireland (IE)

Iceland (IS)

Italy (IT)

Liechtenstein (LI)

Lithuania (LT)

Luxembourg (LU)

Latvia (LV)

Monaco (MC)

Netherlands (NL)

Poland (PL)

Portugal (PT)

Romania (RO)

Sweden (SE)

Slovenia (SI)

Slovakia (SK)

Turkey (TR)

Parties & Representation

Applicants

Boehringer Ingelheim Animal Health USA Inc.

3239 Satellite Blvd, Duluth, GA 30096

Boehringer Ingelheim Vetmedica, Inc.

2621 North Belt Highway, St. Joseph, MO 64506-2002

BOEHRINGER INGELHEIM VETMEDICA, INC.

2621 North Belt Highway, St. Joseph MO 64506-2002

Inventors (5)

Roof, Michael B.

Boehringer Ingelheim Vetmedica, Inc., 2621 North Belt Highway

Eichmeyer, Marc Allan

Boehringer Ingelheim Vetmedica, Inc., 2621 North Belt Highway

Nitzel, Greg

Boehringer Ingelheim Vetmedica, Inc., 2621 North Belt Highway

Hayes, Phillip Wayne

Boehringer Ingelhm Vetmedica, Inc., 2621 North Belt Highway

Schaeffer, Merrill Lynn

Boehringer Ingelheim Vetmedica, Inc., 2621 North Belt Highway

Representatives / Agents

Hoffmann Eitle

Patent- und Rechtsanwälte PartmbB, Arabellastraße 30

HOFFMANN EITLE

Patent- und Rechtsanwälte, Arabellastrasse 4

Hammann, Heinz, et al

Boehringer Ingelheim GmbH Corporate Patents Binger Strasse 173, 55216 Ingelheim am Rhein

Intervet International B.V.

Wim de Körverstraat 35, 5831 AN Boxmeer

Potter Clarkson

Chapel Quarter, Mount Street

Potter Clarkson LLP

The Belgrave Centre, Talbot Street

Janssen, Paulus J. P.

2015-08-20

Opposition in Progress

Legal Status & Event History

Official European Patent Office legal and procedural status changes recorded for this file.

79 Events Recorded

Date	Code	Event Description	Auth
2011-10-05	AC	DIVISIONAL APPLICATION: REFERENCE TO EARLIER APPLICATION	EP
2011-10-05	AK	DESIGNATED CONTRACTING STATES	EP
2011-12-14	RAP1	PARTY DATA CHANGED (APPLICANT DATA CHANGED OR RIGHTS OF AN APPLICATION TRANSFERRED)	EP
2012-05-16	17P	REQUEST FOR EXAMINATION FILED	EP
2013-05-22	17Q	FIRST EXAMINATION REPORT DESPATCHED	EP
2014-12-24	INTG	INTENTION TO GRANT ANNOUNCED	EP
2015-04-08	INTG	INTENTION TO GRANT ANNOUNCED	EP
2015-04-15	INTG	INTENTION TO GRANT ANNOUNCED	EP
2015-08-19	AC	DIVISIONAL APPLICATION: REFERENCE TO EARLIER APPLICATION	EP
2015-08-19	AK	DESIGNATED CONTRACTING STATES	EP
2015-08-19	REG	REFERENCE TO A NATIONAL CODE	EP
2015-08-28	REG	REFERENCE TO A NATIONAL CODE	EP
2015-09-15	REG	REFERENCE TO A NATIONAL CODE	EP
2015-09-09	REG	REFERENCE TO A NATIONAL CODE	EP
2015-09-30	26	OPPOSITION FILED	EP
2015-08-20	REG	REFERENCE TO A NATIONAL CODE	EP
2015-10-01	REG	REFERENCE TO A NATIONAL CODE	EP
2015-11-04	R26	OPPOSITION FILED (CORRECTED)	EP
2015-11-30	REG	REFERENCE TO A NATIONAL CODE	EP
2015-12-07	REG	REFERENCE TO A NATIONAL CODE	EP
2015-11-24	REG	REFERENCE TO A NATIONAL CODE	EP
2015-12-21	REG	REFERENCE TO A NATIONAL CODE	EP
2016-01-25	REG	REFERENCE TO A NATIONAL CODE	EP
2016-01-29	PG25	LAPSED IN A CONTRACTING STATE [ANNOUNCED VIA POSTGRANT INFORMATION FROM NATIONAL OFFICE TO EPO]	EP
2016-02-29	PG25	LAPSED IN A CONTRACTING STATE [ANNOUNCED VIA POSTGRANT INFORMATION FROM NATIONAL OFFICE TO EPO]	EP
2016-04-29	PG25	LAPSED IN A CONTRACTING STATE [ANNOUNCED VIA POSTGRANT INFORMATION FROM NATIONAL OFFICE TO EPO]	EP
2016-05-30	REG	REFERENCE TO A NATIONAL CODE	EP
2016-06-22	26	OPPOSITION FILED	EP
2015-11-16	REG	REFERENCE TO A NATIONAL CODE	EP
2016-07-29	PG25	LAPSED IN A CONTRACTING STATE [ANNOUNCED VIA POSTGRANT INFORMATION FROM NATIONAL OFFICE TO EPO]	EP
2016-08-31	PG25	LAPSED IN A CONTRACTING STATE [ANNOUNCED VIA POSTGRANT INFORMATION FROM NATIONAL OFFICE TO EPO]	EP
2016-01-13	REG	REFERENCE TO A NATIONAL CODE	EP
2016-12-22	REG	REFERENCE TO A NATIONAL CODE	EP
2017-04-19	R26	OPPOSITION FILED (CORRECTED)	EP
2017-05-31	PG25	LAPSED IN A CONTRACTING STATE [ANNOUNCED VIA POSTGRANT INFORMATION FROM NATIONAL OFFICE TO EPO]	EP
2017-06-30	PG25	LAPSED IN A CONTRACTING STATE [ANNOUNCED VIA POSTGRANT INFORMATION FROM NATIONAL OFFICE TO EPO]	EP
2017-08-31	PG25	LAPSED IN A CONTRACTING STATE [ANNOUNCED VIA POSTGRANT INFORMATION FROM NATIONAL OFFICE TO EPO]	EP
2017-12-21	REG	REFERENCE TO A NATIONAL CODE	EP
2018-03-15	REG	REFERENCE TO A NATIONAL CODE	EP
2019-05-08	RAP2	PARTY DATA CHANGED (PATENT OWNER DATA CHANGED OR RIGHTS OF A PATENT TRANSFERRED)	EP
2019-06-26	REG	REFERENCE TO A NATIONAL CODE	EP
2019-08-28	REG	REFERENCE TO A NATIONAL CODE	EP
2019-04-08	APBM	APPEAL REFERENCE RECORDED	EP
2019-04-09	APAH	APPEAL REFERENCE MODIFIED	EP
2019-04-08	APBP	DATE OF RECEIPT OF NOTICE OF APPEAL RECORDED	EP
2019-06-14	APBQ	DATE OF RECEIPT OF STATEMENT OF GROUNDS OF APPEAL RECORDED	EP
2021-04-09	REG	REFERENCE TO A NATIONAL CODE	EP
2015-07-17	GRAA	(EXPECTED) GRANT	EP
2015-07-10	GRAS	GRANT FEE PAID	EP
2015-03-18	GRAP	DESPATCH OF COMMUNICATION OF INTENTION TO GRANT A PATENT	EP
2015-03-11	GRAJ	INFORMATION RELATED TO DISAPPROVAL OF COMMUNICATION OF INTENTION TO GRANT BY THE APPLICANT OR RESUMPTION OF EXAMINATION PROCEEDINGS BY THE EPO DELETED	EP
2015-03-10	GRAP	DESPATCH OF COMMUNICATION OF INTENTION TO GRANT A PATENT	EP
2015-02-28	GRAJ	INFORMATION RELATED TO DISAPPROVAL OF COMMUNICATION OF INTENTION TO GRANT BY THE APPLICANT OR RESUMPTION OF EXAMINATION PROCEEDINGS BY THE EPO DELETED	EP
2014-11-26	GRAP	DESPATCH OF COMMUNICATION OF INTENTION TO GRANT A PATENT	EP
2011-09-02	PUAI	PUBLIC REFERENCE MADE UNDER ARTICLE 153(3) EPC TO A PUBLISHED INTERNATIONAL APPLICATION THAT HAS ENTERED THE EUROPEAN PHASE	EP
2019-02-03	STAA	INFORMATION ON THE STATUS OF AN EP PATENT APPLICATION OR GRANTED EP PATENT	EP
2022-01-31	PGFP	ANNUAL FEE PAID TO NATIONAL OFFICE [ANNOUNCED VIA POSTGRANT INFORMATION FROM NATIONAL OFFICE TO EPO]	EP
2022-02-28	PGFP	ANNUAL FEE PAID TO NATIONAL OFFICE [ANNOUNCED VIA POSTGRANT INFORMATION FROM NATIONAL OFFICE TO EPO]	EP
2019-08-30	PLBP	OPPOSITION WITHDRAWN	EP
2019-02-03	RDAF	COMMUNICATION DESPATCHED THAT PATENT IS REVOKED	EP
2017-03-17	PLAB	OPPOSITION DATA, OPPONENT'S DATA OR THAT OF THE OPPONENT'S REPRESENTATIVE MODIFIED	EP
2016-11-08	PLBB	REPLY OF PATENT PROPRIETOR TO NOTICE(S) OF OPPOSITION RECEIVED	EP
2016-06-22	PLAX	NOTICE OF OPPOSITION AND REQUEST TO FILE OBSERVATION + TIME LIMIT SENT	EP
2016-05-20	PLBI	OPPOSITION FILED	EP
2015-10-02	PLAB	OPPOSITION DATA, OPPONENT'S DATA OR THAT OF THE OPPONENT'S REPRESENTATIVE MODIFIED	EP
2015-08-28	PLBI	OPPOSITION FILED	EP
2022-04-04	PGFP	ANNUAL FEE PAID TO NATIONAL OFFICE [ANNOUNCED VIA POSTGRANT INFORMATION FROM NATIONAL OFFICE TO EPO]	EP
2022-06-01	PGFP	ANNUAL FEE PAID TO NATIONAL OFFICE [ANNOUNCED VIA POSTGRANT INFORMATION FROM NATIONAL OFFICE TO EPO]	EP
2022-10-10	APBU	APPEAL PROCEDURE CLOSED	EP
2022-10-28	RDAF	COMMUNICATION DESPATCHED THAT PATENT IS REVOKED	EP
2022-10-28	RDAE	INFORMATION DELETED RELATED TO DESPATCH OF COMMUNICATION THAT PATENT IS REVOKED	EP
2022-10-28	STAA	INFORMATION ON THE STATUS OF AN EP PATENT APPLICATION OR GRANTED EP PATENT	EP
2022-11-04	RDAG	PATENT REVOKED	EP
2022-10-27	REG	REFERENCE TO A NATIONAL CODE	EP
2022-11-15	REG	REFERENCE TO A NATIONAL CODE	EP
2022-12-07	27W	PATENT REVOKED	EP
2022-12-07	GBPR	GB: PATENT REVOKED UNDER ART. 102 OF THE EP CONVENTION DESIGNATING THE UK AS CONTRACTING STATE	EP
2023-02-15	REG	REFERENCE TO A NATIONAL CODE	EP
2023-02-28	PGFP	ANNUAL FEE PAID TO NATIONAL OFFICE [ANNOUNCED VIA POSTGRANT INFORMATION FROM NATIONAL OFFICE TO EPO]	EP

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- TABLE OF AUTHORITIES

- OPINION OF IOWA ATTORNEY ALLISON KERNDT REGARDING THE HAYES AGREEMENT

- T ABLE OF AUTHORITIES

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US	US2015190498A1	A1	2015-07-09	Espacenet
US	US9669087B2	B2	2017-06-06	Espacenet
US	US2016193320A1	A1	2016-07-07	Espacenet
US	US9987349B2	B2	2018-06-05	Espacenet
US	US2017049875A1	A1	2017-02-23	Espacenet
US	US9610345B2	B2	2017-04-04	Espacenet
WO	WO2007094893A2	A2	2007-08-23	Espacenet
WO	WO2007094893A3	A3	2008-11-06	Espacenet
WO	WO2007094893A9	A9	2016-09-09	Espacenet

Official File Inspection EPC Art. 128 Public Dossier

Complete European Patent Register Dossier (148 Total Documents)

The full inspection file for Application EP11164850 contains 148 total documents, including all notices of opposition, proprietor counter-statements, examination communications, third-party observations, and procedural forms. Below are all major recorded procedural filings and publication specifications.

Open 148-Doc Register Dossier

Dossier Filing

Date: 2021-07-21 Procedure: Examination EPIDOS FREP

Inspect on Register

Use of a PCV2 immunogenic composition for lessening clinical symptoms in pigs

Patent Abstract / Summary

IPC Classifications

Priority Claims

Designated Contracting States (31 EPC States)

Parties & Representation

Applicants

Inventors (5)

Representatives / Agents

Key Procedural Dates

Patent Oppositions

Intervet International BV

Eli Lilly and Company

Eli Lilly and Company

Intervet International BV

Intervet International BV

Legal Status & Event History

Patent & Non-Patent Citations

Cited Patent Documents

Non-Patent Scientific Literature (NPL)

Worldwide Patent Family

Complete European Patent Register Dossier (148 Total Documents)

Recorded Filings & Patent Specifications

European Patent Specification - Granted Patent (B1)

Official European Patent Register Full Dossier

European Patent Application with Search Report (A1)

Revocation of patent

New entry: Despatch of communication that patent is revoked

Deletion: Despatch of communication that patent is revoked

Revocation of the patent

New entry: Decision (+date) in appeal procedure

Oral proceedings

Change: Date of oral proceedings

Deletion: Despatch of minutes of oral proceedings

Change - representative

Opposition withdrawn

New entry: Date of receipt of statement of grounds of an appeal

Change: Appeal number

Change - representative

New entry: Date of receipt of notice of appeal

New entry: Appeal number

Change - applicant

New entry: Despatch of minutes of oral proceedings

New entry: Despatch of communication that patent is revoked

Oral proceedings

Oral proceedings

Lapse of the patent in a contracting state

Lapse of the patent in a contracting state

Lapse of the patent in a contracting state

New entry: Date of oral proceedings

Deletion: Date of oral proceedings

Deletion: Date of cancellation oral proceedings

New entry: Date of cancellation oral proceedings

New entry: Date of oral proceedings

Deletion: Date of oral proceedings

Deletion: Date of cancellation oral proceedings

Change - opposition data/opponent's data or that of the opponent's representative

New entry: Reply of patent proprietor to notice(s) of opposition

Lapse of the patent in a contracting state

Lapse of the patent in a contracting state

Lapse of the patent in a contracting state

Invitation to proprietor to file observations on the notice of opposition

New entry: Communication of a notice of opposition and request to file observations + time limit

Opposition filed

Lapse of the patent in a contracting state

Lapse of the patent in a contracting state

Lapse of the patent in a contracting state

Lapse of the patent in a contracting state

Lapse of the patent in a contracting state

Change - opposition data/opponent's data or that of the opponent's representative

Opposition filed

(Expected) grant

New entry: Receipt of the translation of the claim(s)

New entry: Payment of fee for grant

New entry: Payment of fee for publishing/printing

New entry: Communication of intention to grant a patent

Intention to grant the patent

Deletion - Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO

New entry: Communication of intention to grant a patent

Change - German title