PreOmics GmbH et al. vs. The Brigham and Women’s Hospital, Inc.

Explore the PTAB proceeding IPR2024-01473 filed by PreOmics GmbH et al. on 2024-10-07. This includes filing dates, application numbers, tech centers, patent numbers, and current case status.

Proceeding Overview

Proceeding Number

IPR2024-01473

Filing Date

2024-10-07

Accorded Filing Date

2024-10-07

Institution Decision Date

2025-04-17

Last Modified Date

2026-07-09

Proceeding Type

IPR

Termination Date

2026-03-23

Trial Status

Final Written Decision

Parties & Counsel

Petitioner

PreOmics GmbH et al.

Represented By

Colsher, Patricket al

Patent Owner / Respondent

The Brigham and Women’s Hospital, Inc.

Represented By

Rosato, Michaelet al

Tribunal & Venue

Tribunal

Patent Trial and Appeal Board (USPTO)

Technology Center

TC 1600 - Biotechnology & Organic Chemistry

Patent Information

1 Patent Involved

Respondent Application Number 17215923

Respondent Patent Number 11435360

External Links

Espacenet

Google Patents

Respondent Inventor Omid Farokhzad et al

Respondent Tech Center TC 1600 - Biotechnology & Organic Chemistry

Address and Attorney/Agent Information

61 Registered Practitioners

Power of Attorney & Correspondence

Firm / Entity Name QUARLES & BRADY LLP - ATTN: IP DOCKET

Customer Number 26710

Address 411 E. WISCONSIN AVENUE, SUITE 2400, MILWAUKEE, WI, 53202-4428, UNITED STATES

Attorney / Agent Information

Reg #	Name	Phone
36914	Paul Savereide	612-351-5063
37551	Michael Jaskolski	414-277-5711
38599	Richard Roche	414-277-5805
40634	Christine Hansen	317-399-2829
41756	Terri Flynn	414-277-5229
42533	Therese Finan	202-780-2647
42875	Christopher Mcwhinney	202-372-9605
43193	Jean Tibbetts	414-226-0071
45178	Stephanie Vavra	414-277-5454
47255	Brian Dutton	202-780-2684
47933	Raye Daugherty	414-277-5779
56098	Jack Cook	414-277-5405
56610	Nicholas Schmidbauer	312-715-5072
56736	Thomas Krumenacher	414-277-5199
56972	John Linzer	312-715-5059
58079	Katherine Lobel-Rice	303-268-0066
59057	Stephen Gardner	608-251-5000
59110	Thomas Keating	608-251-5000
59205	Michael Febbo	331-214-6446
59229	Kevin Rizzuto	414-277-5000
60214	Lu Yin	650-752-2436
60978	Daniel Ark	414-277-3061
61522	Tambryn Vanheyningen	608-283-2423
63076	Jonathan Stone	414-277-5000
63251	Michael Curley	520-770-8700
63507	Yakov Sidorin	520-770-8753
63550	James Aquilina Ii	202-780-2637
68176	Wei Yan	312-715-5027
68555	Victoria Cook	602-229-5200
68703	Rory Foster	608-283-2417
68905	Tolga Gulmen	608-283-2421
68994	Lauren Bolcar	202-372-9524
69958	Justin Deangelis	312-715-5168
71189	Michael Santonocito	312-715-2714
71573	Michele Washington	281-216-7654
71915	Michael Piery	414-277-5000
73011	Sarah Cassinis	303-268-0066
76638	Lauren Mccomis	141-427-75348
76773	Justin Doop	312-715-5274
78193	John Jansky	414-277-5287
78456	Rachel Ackerman	312-715-2735
78458	Joseph Ambrose	312-715-5106
78923	Gregory Churney	312-715-2724
79638	Katharine Schulz	952-237-1372
80043	Todd Coffeen Jr.	317-399-2844
80223	Scott Nolan Ii	248-770-7397
80560	Trevor Foster	312-715-5017
80579	Trevor Wilkinson	608-643-9011
80652	Jeffrey Sazama	262-227-8969
80992	Kathryn Madison	303-268-0066
81028	Peter Volberding	414-277-5211
81875	Seth Essendrop	414-277-5239
81924	Mason Baranczyk	414-277-5564
81942	Remy Cooper	202-780-2681
82072	Noah Blue	414-277-500
82085	Theodore Lester	414-277-5528
82393	Margaret Robinson	608-251-5000
82468	Harrison Powell	312-715-5014
82738	Jonathon Young	608-283-2490
82763	Michael Neary	608-251-5000
83007	Alexandra Ballwanz	414-277-5236

Proceeding Documents

110

JUDGMENT Final Written Decision Determining Some Challenged Claims Unpatentable 35 U.S.C. § 318(a) FINAL

2026-03-23 FILING PARTY: BOARD

Download

Other: Hearing transcript OTHER

2026-02-04 FILING PARTY: BOARD

Download

Patent Owner's Updated Exhibit List NOTICE

2026-01-13 FILING PARTY: PATENT OWNER

Download

1042

Petitioners' Demonstratives Exhibit

2026-01-13 FILING PARTY: PETITIONER

Download

Updated Exhibit List NOTICE

2026-01-13 FILING PARTY: PETITIONER

Download

PreOmics GmbH et al. vs. The Brigham and Women’s Hospital, Inc.

Proceeding Overview

Parties & Counsel

Petitioner

PreOmics GmbH et al.

Represented By

Patent Owner / Respondent

The Brigham and Women’s Hospital, Inc.

Represented By

Tribunal & Venue

Patent Information

Address and Attorney/Agent Information

Power of Attorney & Correspondence

Attorney / Agent Information

Proceeding Documents

JUDGMENT Final Written Decision Determining Some Challenged Claims Unpatentable 35 U.S.C. § 318(a) FINAL

Other: Hearing transcript OTHER

Patent Owner's Updated Exhibit List NOTICE

Petitioners' Demonstratives Exhibit

Updated Exhibit List NOTICE

Patent Owner's Demonstratives Exhibit

Patent Owner's Sur-Reply OTHER

ORDER Setting Oral Argument 37 C.F.R. § 42.70 ORDER

Petitioner's Request for Oral Argument OTHER

Patent Owner's Request for Oral Argument OTHER

Patent Owner's Updated Mandatory Notices. NOTICE

Joint Stipulation to Extend Due Date 3 OTHER

HeLa Cells Key Discoveries Exhibit

Cima Deposition Transcript Exhibit

Ma HeLa Cells Exhibit

NOA 109 (annotated) Exhibit

Petitioner Reply to Patent Owner Response REPLYTOOPP

Webster Dictionary (Excerpt) Exhibit

National Library of Med Cell Lysis Exhibit

General Order: Related Matters Updates ORDER

Petitioner's Updated Mandatory Notices NOTICE

Petitioner's Updated Power of Attorney NOTICE

Petitioner's Updated Power of Attorney NOTICE

Notice of Deposition of Dr. Michael J. Cima NOTICE

Declaration of Stephen P. Bosco Exhibit

Notice of Intent to Designate a Provisionally Recognized PTAB Attorney as Back-up Counsel NOTICE

Petitioner's Updated Exhibit List NOTICE

Petitioners' Objections to Evidence NOTICE

Deposition Transcript of Dr. J. Vargas Exhibit

Jianru Stahl-Zeng et al., High Sensitivity Detection of Plasma Proteins by Multiple Reaction Monitoring of N-Glycosites, 6(10) MOLECULAR & CELLULAR PROTEOMICS 1809-1817 (2007) Exhibit

Q14766-4, PEPTIDEATLAS, https://db.systemsbiology.net/sbeams/cgi/PeptideAtlas/GetProtein?atlas_build_id=559&protein_name=Q14766-4&action=QUERY (last visited September 21, 2025) Exhibit

Vinzenz Lange et al., Selective reaction monitoring for quantitative proteomics: a tutorial, 4(222) MOLECULAR SYSTEMS BIOLOGY 1-14 (2008) Exhibit

Summary of EX1009 (Bryk) SBF1 and PIK3R4 Entries Exhibit

Summary of EX1008 (Hu) LTBP Entry Exhibit

Patent Owner Response RESPONSE

Henry H. Heng, HeLa Genome Versus Donor’s Genome, 501 NATURE 167 (2013) Exhibit

Dietrich A. Volmer & Lori Lee Jessome, Ion Suppression: A Major Concern in Mass Spectrometry, 24(5) LCGC NORTH AM. 498-510, available at https://www.chromatographyonline.com/view/ion-suppression-major-concern-mass-spectrometry Exhibit

DONALD VOET, JUDITH G. VOET & CHARLOTTE W. PRATT, FUNDAMENTALS OF BIOCHEMISTRY: LIFE AT THE MOLECULAR LEVEL Section 6-4 (2nd ed. 2006) Exhibit

Summary of EX1007 (Zaccaria) SBF1 Entry Exhibit

Gert Lubec & Leila Afjehi-Sadat, Limitations and Pitfalls in Protein Identification by Mass Spectrometry, 107 CHEMICAL REVIEWS 3568-3584 (2007) Exhibit

CRC HANDBOOK OF CHEMISTRY AND PHYSICS: A READY-REFERENCE BOOK OF CHEMICAL AND PHYSICAL DATA, 7-1 (David R. Lide ed., 72nd ed. 1991) Exhibit

Hasmik Keshishian et al., Quantitative, Multiplexed Assays for Low Abundance Proteins in Plasma by Targeted Mass Spectrometry and Stable Isotope Dilution, 6(12) MOLECULAR & CELLULAR PROTEOMICS 2212-2229 (2007) Exhibit

Summary of EX1007 (Zaccaria) PIK3R4 Entry Exhibit

Alexey I. Nesvizhskii, A Survey of Computational Methods and Error Rate Estimation Procedures for Peptide and Protein Exhibit

DONALD VOET, JUDITH G. VOET & CHARLOTTE W. PRATT, FUNDAMENTALS OF BIOCHEMISTRY: LIFE AT THE MOLECULAR LEVEL Section 19-1 (2nd ed. 2006) Exhibit

Declaration of Dr. M. Cima Exhibit

Summary of EX1007 (Zaccaria) “Other ACs” as alternative to O95248 Exhibit

Curriculum Vitae of Dr. M. Cima Exhibit

Summary of EX1007 (Zaccaria) “Other ACs” as alternative to A0JP11 Exhibit

Shidbas Banerjee & Shyamalava Mazumdar, Electrospray Ionization Mass Spectrometry: A Technique to Access the Information Beyond the Molecular Weight of the Analyte, 2012 INT’L J. ANALYTICAL CHEMISTRY, Article ID 282574 1-40 (2012). Exhibit

Notice of Joint Stipulation to Modify the Scheduling Order NOTICE

Updated Notice of Deposition of Jessica Vargas, PHD. NOTICE

Notice of Deposition of Jessica Vargas, PH.D. NOTICE

Petitioner's Updated Exhibit List NOTICE

Patent Owner's Objections to the Institution Decision NOTICE

Institution Decision: Granting Institution of Inter Partes Review 35 U.S.C. sec. 314 DECISION

Order: SCHEDULING ORDER ORDER

Patent Owner's Updated Mandatory Notices NOTICE

O Farokhzad LinkedIn Exhibit

Claudia Corbo, LINKEDIN Exhibit

Bonislawski 2020 - Seer Closes $55M Funding Round Exhibit

Patent Owner's Preliminary Response POPR

Morteza Mahmoudi, LINKEDIN Exhibit

John E. Blume et al., - Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona Exhibit

Marilena Hadjidemetriou et al. - In Vivo Biomolecule Corona around Blood-Circulating Exhibit