NeoGenomics Laboratories, Inc. vs. Natera, Inc.

Explore the PTAB proceeding IPR2025-00455 filed by NeoGenomics Laboratories, Inc. on 2025-01-15. This includes filing dates, application numbers, tech centers, patent numbers, and current case status.

Proceeding Overview

Proceeding Number

IPR2025-00455

Filing Date

2025-01-15

Accorded Filing Date

2025-01-15

Institution Decision Date

2025-06-12

Last Modified Date

2025-07-13

Proceeding Type

IPR

Termination Date

2025-06-12

Trial Status

Discretionary Denial

Parties & Counsel

Petitioner

NeoGenomics Laboratories, Inc.

Represented By

Arjomand, Mehranet al

Patent Owner / Respondent

Natera, Inc.

Represented By

Doshi, Nishitaet al

Tribunal & Venue

Tribunal

Patent Trial and Appeal Board (USPTO)

Technology Center

TC 1600 - Biotechnology & Organic Chemistry

Patent Information

1 Patent Involved

Respondent Application Number 16288351

Respondent Patent Number 11319596

External Links

Espacenet

Google Patents

Respondent Inventor Joshua BABIARZ et al

Respondent Tech Center TC 1600 - Biotechnology & Organic Chemistry

Address and Attorney/Agent Information

9 Registered Practitioners

Power of Attorney & Correspondence

Firm / Entity Name Natera, Inc. - c/o FOLEY & LARDNER LLP

Customer Number 110711

Address 3000 K STREET N.W., Suite 600, Washington, DC, 20007-5109, UNITED STATES

Attorney / Agent Information

Reg #	Name	Phone
53267	Bernadette Perfect	650-249-909010500
57327	Ashita Doshi	--
61573	Nishita Doshi	760-268-8486
67162	Tianran Yan	202-295-4781
71037	Michael Haggerson	215-656-2467
73614	Luke Burton	909-551-8792
75239	Oyvind Dahle	301-755-4625
76330	Limin Zheng	510-701-3735
78567	Rebecca Estrada	561-927-5264

Proceeding Documents

200

Director Discretionary Decision: Deny RESPONSE

2025-06-12 FILING PARTY: BOARD

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3101

Email Correspondence Exhibit

2025-06-11 FILING PARTY: BOARD

Download

2077

EX2077 - Excerpt of Natera’s Fifth Suppl. ROs to Neo’s Second Set of Interrogatories (Nos. 6-15) (April 4, 2025) Exhibit

2025-05-14 FILING PARTY: PATENT OWNER

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1107

EX1107 - Transcript March 11, 2025 Natera v. NeoGenomics Exhibit

2025-05-14 FILING PARTY: PETITIONER

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1108

EX1108 - Neo's Rule 28(j) Letter Exhibit

2025-05-14 FILING PARTY: PETITIONER

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NeoGenomics Laboratories, Inc. vs. Natera, Inc.

Proceeding Overview

Parties & Counsel

Petitioner

NeoGenomics Laboratories, Inc.

Represented By

Patent Owner / Respondent

Natera, Inc.

Represented By

Tribunal & Venue

Patent Information

Address and Attorney/Agent Information

Power of Attorney & Correspondence

Attorney / Agent Information

Proceeding Documents

Director Discretionary Decision: Deny RESPONSE

Email Correspondence Exhibit

EX2077 - Excerpt of Natera’s Fifth Suppl. ROs to Neo’s Second Set of Interrogatories (Nos. 6-15) (April 4, 2025) Exhibit

EX1107 - Transcript March 11, 2025 Natera v. NeoGenomics Exhibit

EX1108 - Neo's Rule 28(j) Letter Exhibit

EX1109 - Natera Response to Neo's 28(j) Letter Exhibit

Patent Owner's Preliminary Response POPR

Petitioner’s Opposition to Patent Owner’s Request for Discretionary Denial Under 35 U.S.C. § 314(a) RESPONSE

EX2080 - May 14, 2025 Declaration of Sayem Osman Exhibit

EX1110 - NeoGenomics FQ4 2024 Earnings Call Exhibit

EX2079 - Excerpt of Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 24-1324, Non-Confidential Joint Appendix Vol. III of IV (Mar. 18, 2024) Exhibit

EX2075 - Reinert T., Henriksen T., Christensen E., et al., Analysis of plasma cell-free DNA by ultradeep sequencing in patients with stages I to III colorectal cancer, JAMA Oncol. 2019;5(8):1124–1131 Exhibit

EX2076 - Pray, L., DNA Replication and Causes of Mutation, Nature Education 1(1):214 (2008) Exhibit

EX2041 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, First Amended Complaint for Patent Infringement, Dkt. No. 353 (M.D.N.C. Dec. 10, 2024) Exhibit

EX2030 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Plaintiff Natera, Inc.’s Responsive Claim Construction Brief, Dkt. No. 272 (M.D.N.C. Apr. 22, 2024) Exhibit

EX2072 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Plaintiff Natera, Inc.’s Responsive Claim Construction Brief Regarding U.S. Patent No. 11,319,596, Dkt. No. 378 (Feb. 3, 2025) Exhibit

EX2050 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Parties’ Joint Interim Status Report, Dkt. No. 382 (M.D.N.C. Feb. 7, 2025) Exhibit

EX2042 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Defendant NeoGenomics Laboratories, Inc.’s Answer to Plaintiff Natera, Inc.’s First Amended Complaint for Patent Infringement, Dkt. No. 357 (M.D.N.C. Dec. 20, 2024) Exhibit

EX2062 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 24-1324, General Docket (Fed. Cir. 2024) Exhibit

EX2019 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Minute Entry, Dkt. No. 159 (M.D.N.C. Nov. 27, 2023) Exhibit

EX2043 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, NeoGenomics’ Reply in Support of Its Motion for Issuance of Letters of Request for Production of Documents and To Examine Persons Pursuant to Hague Evidence Convention, Dkt. No. 358 (M.D.N.C. Dec. 20, 2024) Exhibit

EX2065 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 24-1324, NeoGenomics Laboratories, Inc.’s Reply Brief, Dkt. No. 39 (Fed. Cir. Mar. 18, 2024) Exhibit

EX2034 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Joint Motion for Temporary Stay of Case Deadlines, Dkt. No. 318 (M.D.N.C. Aug. 21, 2024) Exhibit

EX2038 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Plaintiff’s Reply in Support of Motion for Leave to File First Amended Complaint, Dkt. No. 342 (M.D.N.C. Nov. 29, 2024) Exhibit

EX2055 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Claim Construction Order, Dkt. No. 394 (M.D.N.C. Mar. 17, 2025) Exhibit

EX2064 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 24-1324, Response Brief for Appellee Natera, Inc., Dkt. No. 36 (Fed. Cir. Mar. 11, 2024) Exhibit

EX2004 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Exhibit 1-B – Final Invalidity Claim Chart for U.S. Patent No. 11,319,596 (Mar. 14, 2025) Exhibit

EX2049 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Transcript of Deposition of Dr. Niall Lennon, Dkt. No. 381-1 (M.D.N.C. Feb. 3, 2025) Exhibit

EX2033 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Mandate of the USCA, Dkt. No. 316 (M.D.N.C. Aug. 19, 2024) Exhibit

EX2035 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Stipulated Order and Permanent Injunction, Dkt. No. 329 (M.D.N.C. Sept. 23, 2024) Exhibit

EX2056 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Joint Stipulation and Order Regarding Taking of One Fact Witness Deposition After Close of Fact Discovery, Dkt. No. 399 (M.D.N.C. Mar. 27, 2025) Exhibit

EX2061 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Natera’s Eighth Set of Requests for Production (Nos. 114-122), (M.D.N.C. Mar. 4, 2025) Exhibit

EX2040 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Order Granting Motion to Amend and Adding Deadlines, Dkt. No. 345 (M.D.N.C. Dec. 6, 2024) Exhibit

EX2003 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Exhibit 1-A – Final Invalidity Claim Chart for U.S. Patent No. 11,319,596 (Mar. 14, 2025) Exhibit

EX2016 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Defendant NeoGenomics Laboratories, Inc.’s First Amended Answer, Affirmative Defenses, and Counterclaims to Plaintiff Natera, Inc.’s Complaint for Patent Infringement, Dkt. No. 81 (M.D.N.C. Oct. 6, 2023) Exhibit

EX2012 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Complaint for Patent Infringement, Dkt. No. 1 (M.D.N.C. July 28, 2023) Exhibit

EX2046 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Declaration of Niall Lennon, Ph.D., on Claim Construction, Dkt. No. 374 (M.D.N.C. Jan. 21, 2025) Exhibit

EX2017 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Defendant NeoGenomics Laboratories, Inc.’s Opposition to Plaintiff Natera’s Motion for a Preliminary Injunction, Dkt. No. 89 (M.D.N.C. Oct. 19, 2023) Exhibit

EX2070 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Preliminary Injunction, Dkt. No. 171 (Dec. 27, 2023) Exhibit

EX2068 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Joint Stipulation and Order Regarding Briefing and Discovery Schedule, Dkt. No. 46 (M.D.N.C. Aug. 23, 2023) Exhibit

EX2009 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Exhibit 2-D – Final Invalidity Claim Chart for U.S. Patent No. 11,530,454 (Mar. 14, 2025) Exhibit

EX2008 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Exhibit 2-C – Final Invalidity Claim Chart for U.S. Patent No. 11,530,454 (Mar. 14, 2025) Exhibit

EX2047 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Declaration of Dr. Michael L. Metzker in Support of Plaintiff Natera, Inc.’s Responsive Claim Construction Brief, Dkt. No. 379 (M.D.N.C. Feb. 3, 2025) Exhibit

EX2045 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Defendant NeoGenomics Laboratories, Inc.’s Opening Claim Construction Brief, Dkt. No. 373 (M.D.N.C. Jan. 21, 2025) Exhibit

EX2048 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Declaration of Niall Lennon, Ph.D., in Support of Defendant NeoGenomics Laboratories, Inc.’s Responsive Claim Construction Brief Regarding U.S. Patent No. 11,319,596, Dkt. No. 381 (M.D.N.C. Feb. 3, 2025) Exhibit

EX2036 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Plaintiff Natera’s Motion for Leave to File First Amended Complaint, Dkt. No. 336 (M.D.N.C. Nov. 4, 2024) Exhibit

EX2007 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Exhibit 2-B – Final Invalidity Claim Chart for U.S. Patent No. 11,530,454 (Mar. 14, 2025) Exhibit

EX2063 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 24-1324, NeoGenomics Laboratories, Inc.’s Corrected Opening Brief, Dkt. No. 24 (Fed. Cir. Feb. 13, 2024) Exhibit

EX2020 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Order, Dkt. No. 169 (M.D.N.C. Dec. 27, 2023) Exhibit

EX2073 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Defendant NeoGeonimcs Laboratories, Inc.’s Responsive Claim Construction Brief Regarding U.S. Patent No. 11,319,596, Dkt. No. 380 (Feb. 3, 2025) Exhibit

EX2069 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Defendant NeoGenomics Laboratories, Inc.’s Second Amended Answer, Affirmative Defenses, and Counterclaims to Plaintiff Natera, Inc.’s Complaint for Patent Infringement, Dkt. No. 128 (Oct. 20, 2023) Exhibit

Notice: Extending Deadline for Discretion Briefing NOTICE

EX2026 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Defendant’s Initial Invalidity Contentions, Dkt. No. 263-5 (M.D.N.C. Apr. 8, 2024) Exhibit

EX2010 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Defendant’s Final Invalidity Contentions (Redacted) (M.D.N.C. July 11, 2024) Exhibit

EX2037 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Defendant NeoGenomics Laboratories, Inc.’s Opposition and Conditional Consent to Natera’s Motion for Leave to File First Amended Complaint, Dkt. No. 340 (M.D.N.C. Nov. 15, 2024) Exhibit

EX2057 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Natera’s Sixth Set of Interrogatories (Nos. 25-29), (M.D.N.C. June 18, 2024) Exhibit

EX2028 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Declaration of David I. Smith, Ph.D. on Claim Construction, Dkt. No. 264-5 (M.D.N.C. Apr. 8, 2024) Exhibit

EX2031 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Claim Construction Order, Dkt. No. 280 (M.D.N.C. May 17, 2024) Exhibit

EX2058 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, NeoGenomics Laboratories, Inc.’s Third Set of Interrogatories (Nos. 16-25) (Redacted), (M.D.N.C. June 18, 2024) Exhibit

EX2066 - Explanation of Selected Terms, United States District Courts National Judicial Caseload Profile Exhibit

EX2052 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Transcript of Deposition of Dr. Michael Metzker, Dkt. No. 388-1 (M.D.N.C. Feb. 27, 2025) Exhibit

EX2039 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Plaintiff’s Natera, Inc.’s Disclosure of Asserted Claims and Preliminary Infringement Contentions (redacted), Dkt. No. 342-2 (M.D.N.C. Nov. 29, 2024) Exhibit

EX2024 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Plaintiff Natera, Inc.’s Opening Claim Construction Brief, Dkt. No. 262 (M.D.N.C. Apr. 8, 2024) Exhibit

Patent Owner's Brief in Support of Discretionary Denial RESPONSE

EX2022 - Natera, Inc. v. NeoGenomics Laboratories, Inc., No. 1:23-cv-00629, Joint Claim Construction Statement, Dkt. No. 249 (M.D.N.C. Mar. 15, 2024) Exhibit