Bonerge Lifescience (Hunan) Co., Ltd. vs. Nanjing Nutrabuilding Bio-Tech Co., Ltd.

Explore the PTAB proceeding IPR2025-01593 filed by Bonerge Lifescience (Hunan) Co., Ltd. on 2025-09-26. This includes filing dates, application numbers, tech centers, patent numbers, and current case status.

Proceeding Overview

Proceeding Number

IPR2025-01593

Filing Date

2025-09-26

Accorded Filing Date

2025-09-26

Institution Decision Date

2026-03-17

Last Modified Date

2026-09-10

Proceeding Type

IPR

Termination Date

—

Trial Status

Trial Instituted

Parties & Counsel

Petitioner

Bonerge Lifescience (Hunan) Co., Ltd.

Represented By

Handy, John

Patent Owner / Respondent

Nanjing Nutrabuilding Bio-Tech Co., Ltd.

Represented By

Nielsen, Market al

Tribunal & Venue

Tribunal

Patent Trial and Appeal Board (USPTO)

Technology Center

TC 1600 - Biotechnology & Organic Chemistry

Patent Information

1 Patent Involved

Respondent Application Number 15491933

Respondent Patent Number 10278961

External Links

Espacenet

Google Patents

Respondent Inventor Ryan Lowery et al

Respondent Tech Center TC 1600 - Biotechnology & Organic Chemistry

Address and Attorney/Agent Information

6 Registered Practitioners

Power of Attorney & Correspondence

Firm / Entity Name SCHEEF & STONE, L.L.P.

Customer Number 52529

Address 500 N. Akard, Suite 2700, DALLAS, TX, 75201, UNITED STATES

Attorney / Agent Information

Reg #	Name	Phone
38324	Jack Stone Jr	214-706-4207
41748	John Fischer	214-706-4201
45936	Robin Barnes	214-706-4233
52068	Mark Nielsen	214-472-2100
64494	Keith Rawlins	214-367-6000
70409	Michael Schofield	469-855-3378

Proceeding Documents

200

Order: MODIFIED SCHEDULING ORDER ORDER

2026-09-10 FILING PARTY: BOARD

Download

Patent Owner Objections to Evidence Submitted in Reply OTHER

2026-09-08 FILING PARTY: PATENT OWNER

Download

1021

Ni Yanxia et al., Therapeutic effect of berberine on 60 patients with Type II diabetes mellitus and experimental research. CJIM (1988) (with English Abstract). Exhibit

2026-08-31 FILING PARTY: PETITIONER

Download

1023

Supplemental Declaration of Dr. Ronald J. Shebuski, Sr. Exhibit

2026-08-31 FILING PARTY: PETITIONER

Download

1024

Declaration of Hua Chen l in Support of Petitioner's Reply Exhibit

2026-08-31 FILING PARTY: PETITIONER

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Bonerge Lifescience (Hunan) Co., Ltd. vs. Nanjing Nutrabuilding Bio-Tech Co., Ltd.

Proceeding Overview

Parties & Counsel

Petitioner

Bonerge Lifescience (Hunan) Co., Ltd.

Represented By

Patent Owner / Respondent

Nanjing Nutrabuilding Bio-Tech Co., Ltd.

Represented By

Tribunal & Venue

Patent Information

Address and Attorney/Agent Information

Power of Attorney & Correspondence

Attorney / Agent Information

Proceeding Documents

Order: MODIFIED SCHEDULING ORDER ORDER

Patent Owner Objections to Evidence Submitted in Reply OTHER

Ni Yanxia et al., Therapeutic effect of berberine on 60 patients with Type II diabetes mellitus and experimental research. CJIM (1988) (with English Abstract). Exhibit

Supplemental Declaration of Dr. Ronald J. Shebuski, Sr. Exhibit

Declaration of Hua Chen l in Support of Petitioner's Reply Exhibit

Amazon.com product listing for Nature's Fusions dihydroberberine (ASIN B0CWC6F56X), captured August 30, 2026 Exhibit

Sofianos Andrikopoulos et al., Evaluating the glucose tolerance test in mice, American Journal of Physiology-Endocrinology and Metabolism, (2008) E1323-1332. Exhibit

Ex parte Bernstein, Appeal No. 2014-007316, Appl. No. 13/197,581 (P.T.A.B. Aug. 27, 2015) (Decision on Appeal) Exhibit

Petitioners' Reply Briefing REPLYTOOPP

Blog entitled “GlucoVantage: Dihydroberberine for Superior Insulin Sensitivity,” by Mike Roberto (January 15, 2020), available at https://blog.priceplow.com/supplement-ingredients/glucovantage. Exhibit

Appellant's Appeal Brief, U.S. Patent Application No. 13/197,581 (Ex parte Bernstein), with Exhibits A-G Exhibit

Ex. 1019 - 2026.7.1 Hua Chen Notice to Intent PHV Exhibit

Ex. 1018 - 2026.7.1 Jason Xu Notice to Intent PHV - Exhibit

Petitioner's Notice of Intent to Designate Provisionally Recognized PTAB Attorney Hua Chen as Back Up Counsel Under 37 C.F.R. Section 42.10(c) NOTICE

Declaration of Hua Chen in Support of Petitioner's Notice of Intent to Designate Provisionally Recognized PTAB Attorney Hua Chen as Back Up Counsel Under 37 C.F.R. Section 42.10(c) OTHER

Petitioner's Notice of Intent to Designate Provisionally Recognized PTAB Attorney Jason Xu as Back Up Counsel Under 37 C.F.R. Section 42.10(c) NOTICE

Declaration of Jason Xu in Support of Petitioner's Notice of Intent to Designate Provisionally Recognized PTAB Attorney Jason Xu as Back Up Counsel Under 37 C.F.R. Section 42.10(c) OTHER

PricePlow Blog, Nov. 30, 2023 Exhibit

Patent Owner's Motion to Seal Submitted in Connection with Response to Petition MOTION

Frazier-Price 1998 Article Exhibit

ccof.org Doc Exhibit

ATCC - L6 Cell information Exhibit

Redacted Version of Exh. 2144 Exhibit

Vinatura web Docs Exhibit

Bonerge website Docs Exhibit

NIH Docs Exhibit

Redacted Version of Exh. 2140 Exhibit

iherb.com Docs Exhibit

Palmer and Bonner 2007 Book Excerpts Exhibit

Spins.com - Supplysidesj - agfunder docs Exhibit

Redacted Version of Exh. 2138 Exhibit

Robinson 2015 Article Exhibit

Maubon 2007 Article Exhibit

Fryar-CDC 2016 Article Exhibit

Redacted Version of Exh. 2173 Exhibit

Walmart.com Doc bundle Exhibit

Vinatura Store Website Jan. 23, 2026 Exhibit

Nature's Fusions Web Pages Exhibit

Clarfield Review The Discovery of Insulin Twenty fifth Anniversary Bliss 2009 Exhibit

PricePlow Blog Docs Exhibit

cbinsights.com Doc Exhibit

Clinicaltrials.gov Doc Exhibit

Curriculum Vitae of Dr. Louis J. DeFilippi, Ph.D. Exhibit

NNB Documents 131-142 Exhibit

patsnap doc re Bonerge Exhibit

Advancedlabsinc.com etc Bundled Docs Exhibit

prlabs and nutraingredients web Docs Exhibit

Redacted Version of Exh. 2126 Exhibit

USPTO Trademark Docs Exhibit

RMB exchange rate docs Exhibit

NIH WaPo etc Docs Exhibit

PubMed docs Exhibit

intimaterose.com Doc Exhibit

Nathan 2007 Article Exhibit

mdpi.com Doc Exhibit

Peak Performance Blog Nov. 10, 2025 Exhibit

Rao 2004 Article Exhibit

Andrikopoulos Article Exhibit

NNB 8-14, 119-126, 127-130, 131-142 Exhibit

Redacted Version of Exh. 2143 Exhibit

Blanchard-Smoliga 2015 Article Exhibit

Curriculum Vitae of Stephen Holzen Exhibit

Amazon.com Doc bundle Exhibit

Petition for IPR and Assignments Exhibit

Raccah et al. 2017 Article Exhibit