Guardant Health, Inc. vs. Tempus AI, Inc.

Explore the PTAB proceeding IPR2026-00185 filed by Guardant Health, Inc. on 2025-12-30. This includes filing dates, application numbers, tech centers, patent numbers, and current case status.

Proceeding Overview

Proceeding Number

IPR2026-00185

Filing Date

2025-12-30

Accorded Filing Date

2025-12-30

Institution Decision Date

2026-04-28

Last Modified Date

2026-06-18

Proceeding Type

IPR

Termination Date

2026-04-28

Trial Status

Discretionary Denial

Parties & Counsel

Petitioner

Guardant Health, Inc.

Represented By

Rosato, Michaelet al

Patent Owner / Respondent

Tempus AI, Inc.

Represented By

Powers, Treyet al

Tribunal & Venue

Tribunal

Patent Trial and Appeal Board (USPTO)

Technology Center

TC 2600 - Communications

Patent Information

1 Patent Involved

Respondent Application Number 16732242

Respondent Patent Number 10991097

External Links

Espacenet

Google Patents

Respondent Inventor Stephen Yip et al

Respondent Tech Center TC 2600 - Communications

Address and Attorney/Agent Information

77 Registered Practitioners

Power of Attorney & Correspondence

Firm / Entity Name MARSHALL, GERSTEIN & BORUN LLP

Customer Number —

Address 233 SOUTH WACKER DRIVE, 6300 WILLIS TOWER, CHICAGO, IL, 60606-6357, UNITED STATES

Attorney / Agent Information

Reg #	Name	Phone
28491	James Zeller	312-474-6300
31879	Jeffrey Sharp	312-474-6300
32254	Richard Labarge	312-474-6300
32361	James Napoli	312-474-6300
34824	Robert Gerstein	312-474-6300
35302	Greta Noland	312-474-6300
37641	Roger Heppermann	312-474-6300
38153	David Gass	312-474-6300
38359	Michael Weiner	312-474-6300
39257	Jeremy Kriegel	312-474-6300
39811	David Read	312-474-6300
40725	William Merkel	312-474-6300
43032	Elaine Ramesh	312-474-6300
43136	Gregory Smith	312-474-6300
43603	Joshua Elliott	312-474-6300
43848	Sandip Patel	312-474-6300
44684	Kevin Flowers	312-474-6300
45790	Heather Kissling	312-474-6300
45887	Randall Rueth	312-474-6300
46130	Andrew Lawrence	312-474-6300
46674	Meggan Duffy	312-474-6300
47678	Mark Izraelewicz	312-474-6300
47970	Paul Stephens	312-474-6300
48484	Sharon Sintich	312-474-6300
48642	Michael Muczynski	312-474-6300
51584	Pamela Cox	312-474-6300
52664	Eric Brusca	312-474-6300
53066	Lynn Janulis	312-474-6300
53171	John Labbe	312-474-6300
53379	Katherine Neville	312-474-6300
55064	Michael Chinlund	312-474-6300
56301	Jeanne Brashear	312-474-6300
57712	Shelley Danek	312-474-6300
58495	Michael Furmanek	312-474-6300
60674	Ryan Phelan	312-474-6300
61082	Matthew Carey	312-474-6300
61192	Daniel Chavka	312-474-6300
61681	Jeremy Protas	312-474-6300
61889	Steven Parks	312-474-6300
62856	Raymond Ricordati Iii	312-474-6617
63549	Michael Allikian	312-474-6300
64050	Andrew Bateman	402-933-0304
64192	Joseph Sakevich	312-474-6300
64514	Lilian Ficht	312-474-6300
64594	Jennifer Burnette	312-474-6300
64635	Derek Barnett	312-474-6300
64864	Katharine Su	312-474-6300
65275	Ryan Schermerhorn	312-474-6300
66014	Matthew Jorge	312-474-6300
66234	Tiffany Gehrke	312-474-6300
66337	William Samore	312-474-6641
66913	Vyacheslav Elkin	312-474-6300
67464	Theresa Stadheim	612-743-4498
69622	Jacqueline Felda	312-474-6300
69942	Conor Hunt	312-474-6300
71172	Cameron Pick	312-474-6300
71868	Nicholas Terrell	312-474-6300
74556	Jonathan Hughley	312-474-6622
74659	Michael Anderson	312-474-6300
74672	Noah Tilton	1-302-355-4243
74887	Shannon Mastick	224-805-6800
75141	Alden Voelker	312-423-3444
77550	Robert Jacobson	312-423-3432
77681	Thomas Burns	773-687-8577
78358	Kevin Piotrowski	312-474-9567
78390	Stephen Kudla	312-474-9569
78795	Stefan Brooks	312-474-6300
79836	Robert Johnson	312-423-3464
80725	Carolyn Clark	859-492-8926
81071	Alan Shramuk	312-474-6300
81252	Gabrielle Sue	650-888-2336
82273	Qixuan Wang	312-423-3443
82378	Matthew Nealon	312-423-3453
82451	Ria Patel	813-528-6877
82524	Ryan Slechta	312-474-6300
83235	Christopher Zahn	312-423-3459
L1405	Shuang Liu	312-423-3457

Proceeding Documents

Notice of Refund NOTICE

2026-06-18 FILING PARTY: BOARD

Download

Petitioner's Request for Refund OTHER

2026-06-09 FILING PARTY: PETITIONER

Download

Director Discretionary Decision: Deny RESPONSE

2026-04-28 FILING PARTY: BOARD

Download

2007

EX2007 - Statutory Disclaimer Exhibit

2026-04-13 FILING PARTY: PATENT OWNER

Download

Patent Owner's Preliminary Response POPR

2026-04-13 FILING PARTY: PATENT OWNER

Download

Guardant Health, Inc. vs. Tempus AI, Inc.

Proceeding Overview

Parties & Counsel

Petitioner

Guardant Health, Inc.

Represented By

Patent Owner / Respondent

Tempus AI, Inc.

Represented By

Tribunal & Venue

Patent Information

Address and Attorney/Agent Information

Power of Attorney & Correspondence

Attorney / Agent Information

Proceeding Documents

Notice of Refund NOTICE

Petitioner's Request for Refund OTHER

Director Discretionary Decision: Deny RESPONSE

EX2007 - Statutory Disclaimer Exhibit

Patent Owner's Preliminary Response POPR

U.S. Patent No. 10,957,041 Exhibit

Petitioner's Opposition to Patent Owner's Discretionary Denial Request RESPONSE

U.S. Patent No. 19,360,756 Exhibit

U.S. Patent No. 18,433,240 Exhibit

Statutory Disclaimer in U.S. Patent No. 10,991,097 Exhibit

EX2002 - Judgement (325-cv-06622) Exhibit

EX2005 - Stipulation and Final Judgement (325-cv-06622) Exhibit

EX2004 - Stipulation Waiving Rights (325-cv-06622) Exhibit

Patent Owner's Discretionary Denial Brief RESPONSE

EX2001 - Order Granting Defendant’s Motion to Dismiss (325-cv-06622) Exhibit

EX2006 - Email Exchange Exhibit

EX2003 - Termination Order (325-cv-06622) Exhibit

Petitioner's Updated Mandatory Notices NOTICE

Patent Owner's Mandatory Notices NOTICE

Patent Owner's Power of Attorney NOTICE

Notice of Accepting Corrected Petition NOTICE

International Publication No. WO 2015/124737 A1 to Sebastiao, et al. Exhibit

Notice filing date accorded to Petition NOTICE

Thouis R. Jones, et al., “Voronoi-based segmentation of cells on image manifolds.” International Workshop on Computer Vision for Biomedical Image Applications. Exhibit

Mahalakshmi Ravi, et al., “Expression of α-smooth Muscle Actin in Benign Exhibit

Thouis R. Jones, et al., “Voronoi-based segmentation of cells on image Exhibit

Notice: Power of Attorney NOTICE

Jocelyn Barker, et al., “Automated Classification of Brain Tumor Type Exhibit

International Publication No. WO 2015/124737 A1 to Sebastiao, et al. Exhibit

Qiang Du, et al., “Centroidal Voronoi tessellations: Applications Exhibit

Thomas J. Kindt, et al., Kuby Immunology, 2007 (6th Ed.) Exhibit

Jun Kong, et al., “Computer-aided Evaluation of Neuroblastoma on Whole-slid Exhibit

Plaintiff Tempus AI, Inc.’s Complaint for Patent Infringement, Tempus AI, Exhibit

Nemanja Rajković, et al., “The Pan-cytokeratin Staining Intensity and Fract Exhibit

Petition: as filed PETITION

Zeta Corp. Pancytokeratin brochure Exhibit

U.S. Patent No. 10,991,097 Exhibit

Defendant Guardant Health Inc.’s Memorandum of Points and Authorities Exhibit

U.S. Patent Appl. Pub. No. 2016/0063724 Exhibit

John D. Bancroft, ed. “Theory and Practice of Histological Techniques Exhibit

Papanikolopoulos Declaration Exhibit

Peter J. Burt, et al., “The Laplacian Pyramid as a Compact Image Code.” Exhibit

Brandon D. Gallas et al. “eeDAP: an Evaluation Environment for Digital Exhibit

Songfan Yang, et al., “Multi-scale Recognition with DAG-CNNs.” Proceedings Exhibit

Giuseppe Musumeci “Past, Present and Future: Overview on Histology Exhibit

U.S. Patent Publication No. 2016/0042511 A1 to Chukka et al. Exhibit

Papanikolopoulos CV Exhibit

Michael J. Gerdes, et al. “Highly Multiplexed Single-Cell Analysis Exhibit

’097 Patent Prosecution History (Part 1) Exhibit

Metin N. Gurcan et al., “Histopathological image analysis: A review.” IEEE Exhibit

Liron Pantanowitz, et al., “Twenty Years of Digital Pathology: An Overview Exhibit

Keith E. Steele, et al., “Measuring Multiple Parameters of CD8+ Tumor Exhibit

Michael Barnes, et al., “Abstract P5-03-08: Development of a Histology-base Exhibit

Thomas Mentzel, et al., “Cutaneous Myoepithelial Neoplasms: Clinicopatholog Exhibit

Xipeng Pan et al., “Cell Detection in Pathology and Microscopy Images Exhibit

Emilio Garcia, et al., “Automatic Lymphocyte Detection on Gastric Cancer IH Exhibit

Michal Zamecnik, “Epithelioid Hemangioendothelioma with Actin+/Cytokeratin+ Exhibit

Mami Murakami, et al., “Docetaxel Conjugate Nanoparticles that Target Exhibit

Peter W. Hamilton et al. “Digital Pathology and Image Analysis in Tissue Exhibit

’097 Patent Prosecution History (Part 2) Exhibit

Sahirzeeshan Ali et al., “Segmenting Multiple Overlapping Objects Via a Hyb Exhibit