BeiGene USA, Inc. et al. vs. Pharmacyclics LLC

Explore the PTAB proceeding PGR2024-00009 filed by BeiGene USA, Inc. et al. on 2023-11-01. This includes filing dates, application numbers, tech centers, patent numbers, and current case status.

Proceeding Overview

Proceeding Number

PGR2024-00009

Filing Date

2023-11-01

Accorded Filing Date

2023-11-06

Institution Decision Date

2024-05-01

Last Modified Date

2025-09-29

Proceeding Type

PGR

Termination Date

2025-04-29

Trial Status

Final Written Decision

Parties & Counsel

Petitioner

BeiGene USA, Inc. et al.

Represented By

Berl, David

Patent Owner / Respondent

Pharmacyclics LLC

Represented By

Frazier, Davidet al

Tribunal & Venue

Tribunal

Patent Trial and Appeal Board (USPTO)

Technology Center

TC 1600 - Biotechnology & Organic Chemistry

Patent Information

1 Patent Involved

Respondent Application Number 16926280

Respondent Patent Number 11672803

External Links

Espacenet

Google Patents

Respondent Inventor Joseph J. Buggy

Respondent Tech Center TC 1600 - Biotechnology & Organic Chemistry

Address and Attorney/Agent Information

69 Registered Practitioners

Power of Attorney & Correspondence

Firm / Entity Name FOLEY HOAG, LLP (w/PIR) - PATENT GROUP, Seaport West

Customer Number 136314

Address 155 SEAPORT BLVD, BOSTON, MA, 02210, UNITED STATES

Attorney / Agent Information

Reg #	Name	Phone
36207	Amy Mandragouras	617-573-4700
36373	Allan Brookes	508-733-3757
36683	Deann Smith	617-832-1000
38327	Peter Sullivan	646-927-5510
40060	John Lanza	617-342-4084
44075	Portia Chen	847-937-8272
44554	Matthew Brady	714-246-4788
44719	Dana Gordon	617-832-1000
44735	David Halstead	617-832-1754
46488	Hathaway Russell	617-832-1000
46652	Stephen D'Amico	224-440-7242
46789	Mark Hyman	847-937-8941
47413	Eric Baude	847-938-8389
47717	Renee Kosslak	650-454-2338
48155	Amy Klann	212-812-0329
48591	Tara Seshadri	508-688-8058
51582	Johanna Corbin	847-935-7956
55863	Glen Gesicki	847-937-3810
58113	Rosaleen Walsh	617-832-7123
59404	Lorenz Siddiqi	714-246-3425
61483	Maya Elbert	212-326-3939
61671	Stephen Kenny	646-927-5570
64000	Janine Ladislaw	617-832-1790
65077	Brendan Jones	617-832-1267
65244	Philip Choi	617-832-1743
65390	Joshua Matloff	617-832-1775
66389	Erik Huestis	212-812-0325
66931	Thi Dio	617-832-1729
67983	David Surry	646-927-5515
68376	Xianfeng Xu	202-261-7321
68559	Matthew Jonsen	303-352-1178
68989	Lucas Watkins	212-812-0335
70485	Nicholas Leonard	847-938-6268
70919	Michael Montgomery	847-937-7418
71358	Wendy Ballard	919-610-1900
71655	Laura Wzorek	617-832-1727
71813	Erin Foley	858-775-3361
72455	Jyoti Tibrewala	617-832-7186
73462	Tracy Vrablik	617-832-1296
73600	Ariana Harris	617-832-1141
74331	Allison Gilder	617-832-1782
75183	David Shore	617-832-1714
75780	Mi Cai	314-562-3271
76451	Yunjun Guo	314-378-6012
76844	Alexander Chatterley	617-832-1786
77026	Allisyn Monteleone	304-539-2030
77152	Mohanad Mossalam	617-832-3072
77238	Benjamin Vaughan	617-832-1740
77986	Lee Chedister	202-899-3081
78068	Lawrence Tardibono	212-812-0303
78493	Alexander Berne	212-812-0312
78828	Tatiana Headrick	617-832-1774
79716	Vincenzo Dimonaco	203-752-8188
80234	Samantha Devenport	617-832-1194
80762	Taylor Canady	412-463-2202
81257	Tesia Chciuk	202-371-2600
82205	Eun Jin Hong	617-832-1174
82343	Lucas Freeman	617-832-3092
82356	Vicente Nunez	617-832-3082
82390	Yaron Marciano	212-812-0365
82486	Emily Yasharpour	212-812-0328
82632	Katherine Baker	212-812-0321
82692	Lillian Schmaltz	617-832-1149
82819	Caroline Werlang	617-832-3084
83018	Konstantinos Mylonas	212-812-0367
83224	Austin Hachey	413-824-0237
83456	Sophie Tanker	720-782-5083
83764	Shejla Pollozi	212-812-0334
83941	Jordan Isaacs	617-832-1243

Proceeding Documents

200

Order Denying Director Review of Final Written Decision MOTION

2025-07-17 FILING PARTY: BOARD

Download

Authorized Response to Director Review Request (6.6.25) OTHER

2025-06-06 FILING PARTY: PETITIONER

Download

3100

Ex. 3100 Counsel email for Authorized Response Exhibit

2025-05-30 FILING PARTY: BOARD

Download

Patent Owner's Request for Director Review REQUEST

2025-05-29 FILING PARTY: PATENT OWNER

Download

Updated Mandatory Notice (5.29.25) NOTICE

2025-05-29 FILING PARTY: PETITIONER

Download

BeiGene USA, Inc. et al. vs. Pharmacyclics LLC

Proceeding Overview

Parties & Counsel

Petitioner

BeiGene USA, Inc. et al.

Represented By

Patent Owner / Respondent

Pharmacyclics LLC

Represented By

Tribunal & Venue

Patent Information

Address and Attorney/Agent Information

Power of Attorney & Correspondence

Attorney / Agent Information

Proceeding Documents

Order Denying Director Review of Final Written Decision MOTION

Authorized Response to Director Review Request (6.6.25) OTHER

Ex. 3100 Counsel email for Authorized Response Exhibit

Patent Owner's Request for Director Review REQUEST

Updated Mandatory Notice (5.29.25) NOTICE

Corrected Final Written Decision Determining All Challenged Claims Unpatentable FINAL

E-mail regarding Final Written Decision Exhibit

Judgment Final Written Decision FINAL

Updated Mandatory Notice (3.20.25) NOTICE

Ex. 2124 Supervisory Patent Examiner Response - Return for Certificate of Correction Exhibit

Patent Owner's Updated Exhibit List NOTICE

Other: Hearing transcript OTHER

Patent Owner's Demonstratives part 1 of 2 OTHER

Patent Owner's Demonstratives part 2 of 2 OTHER

Petitioners' Demonstrative Exhibits OTHER

ORDER Granting Petitioner’s Motion for Admission Pro Hac Vice of Kevin Hoagland-Hanson 37 C.F.R. § 42.10 ORDER

LEAP Practitioner Request and Verification Form (Petitioner) NOTICE

Motion for PHV Admission (Kevin Hoagland-Hanson) MOTION

Joint Stipulation to Extend Service Date of Demonstrative Exhibits OTHER

ORDER Setting Oral Argument 37 C.F.R. § 42.70 ORDER

Patent Owner's Request for Oral Argument OTHER

Petitioners' Request for Oral Argument MOTION

Declaration ISO Motion for PHV Admission (Kevin Hoagland-Hanson) Exhibit

Petitioners' Unopposed Motion for Pro Hac Vice Admission of Kevin Hoagland-Hanson MOTION

Petitioners' Unopposed Motion for Pro Hac Vice Admission of Kevin Hoagland-Hanson Pursuant to 37 CFR 42.10(c) MOTION

Ex. 2119 Veal Dep. (11.22.2024) Exhibit

Ex. 2120 Veal, ch. 16 in Kinase Inhibitor Drugs (Veal Dep. Ex. 1) Exhibit

Ex. 2118 Showalter Dep. (11.08.2024) Exhibit

Ex. 2122 Eck Deposition Errata Exhibit

Ex. 2123 Scott Deposition Errata Exhibit

Ex. 2121 Adams et al., ch. 2 in Protein Crystallography (2004) (Veal Dep. Ex. 2) Exhibit

Patent Owner's Sur-Reply OTHER

Updated Mandatory Notice NOTICE

Amended POA NOTICE

Petitioners' Updated Exhibit List NOTICE

Patent Owner's Objections to Petitioner's Evidence OTHER

Petitioners' Updated Exhibit List NOTICE

Patent Owner's Notice of Deposition of James Veal NOTICE

Eck Deposition Exhibit 4 Exhibit

WIPO Publication No. WO 2016/007185A1 Exhibit

WIPO Publication No. WO 2014/173289A1 Exhibit

Elizabeth H. Krenske et. al., “Transition States and Energetics of Nucleophilic Additions of Thiols to Substituted a,β-Unsaturated Ketones: Substituent Effects Involve Enone Stabilization, Product Branching, and Solvation” Exhibit

Eck Deposition Exhibit 3 Exhibit

Eck Deposition Exhibit 5 Exhibit

Kun-Yi Hsin, et. al., “Combining Machine Learning Systems and Multiple Docking Simulation Packages to Improve Docking Prediction Reliability for Network Pharmacology” Exhibit

“What is the difference between GlideScore and Emodel, and which should I use for ranking poses?” Exhibit

Petitioner's Reply to Patent Owner's Response REPLYTOOPP

Eck Deposition Exhibit 2 Exhibit

Reply Declaration of James M. Veal, Ph.D. Exhibit

David Ramirez and Julio Caballero, “Is it Reliable to Use Common Molecular Docking Methods for Comparing the Binding Affinities of Enantiomer Pairs for Their Protein Target?” Exhibit

Supplementary Material for the manuscript “Numerical Errors and Chaotic Behavior in Docking Simulations” Exhibit

Deposition Transcript of Stephen E. Spurgeon Exhibit

Ermias Mergia Terefe and Arabinda Ghosh, “Molecular Docking, Validation, Dynamics Simulations, and Pharmacokinetic Prediction of Phytochemicals Isolated From Croton dichogamus Against the HIV-1 Reverse Transcriptase” Exhibit

Structure E2, 803 Patent (Glide Modeling) Exhibit

Syed Awais Attique, et. al. “A Molecular Docking Approach to Evaluate the Pharmacological Properties of Natural and Synthetic Treatment Candidates for Use against Hypertension" Exhibit

Structure E4, 803 Patent (Glide Modeling) Exhibit

Deposition Transcript of Michael J. Eck, M.D., Ph.D, Exhibit

RCSB PDB - 5TR6_ Discovery of TAK-659, an Orally Available Investigational Inhibitor of Spleen Tyrosine Kinase (SYK) Exhibit

Dariusz Plewczynski, et. al., “Can We Trust Docking Results? Evaluation of Seven Commonly Used Programs on PDBbind Database” Exhibit

Zanubrutinib (Glide Modeling) Exhibit

Compound 30, 446 Patent (Glide Modeling) Exhibit

Sara Shamsian, et. al., “Bencchmarking different docking protocols for predicting the binding poses of ligands complexed with cyclooxygenase enzymes and screening chemical libraries” Exhibit

“Docking and Scoring”, Schrödinger, Inc. Exhibit

Formula I, 820 Patent (Glide Modeling) Exhibit

Dian Jiao, et. al. “Calculation of protein-ligand binding free energy by using a polarizable potential” Exhibit